His father had been summoned to Parliament as Lord Strange in 1482 in right of his wife, but predeceased his father. Derby succeeded his grandfather in the earldom and barony of Stanley in 1504 and in 1514 he also inherited the baronies of Strange and Mohun from his mother. He married Anne Hastings, daughter of Edward Hastings, 2nd Baron Hastings, in circa 1507.
Lord Derby died in May 1521 and was succeeded in his titles by his son Edward. His line of the Stanley family failed on the death of James Stanley, 10th Earl of Derby, in 1736, when the Earldom passed on to a descendant of his younger brother Sir James Stanley, who founded the branch of the family known as the "Stanleys of Bickerstaffe".
Lord Derby died in May 1521 and was succeeded in his titles by his son Edward. His line of the Stanley family failed on the death of James Stanley, 10th Earl of Derby, in 1736, when the Earldom passed on to a descendant of his younger brother Sir James Stanley, who founded the branch of the family known as the "Stanleys of Bickerstaffe".
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